Appointment of hormonal drugs often scares people. Hormones formed around a lot of myths. But most of them are wrong, especially concerned Prometrium.

Myth 1: Prometrium – a special pill for women.
No. Prometrium is a medication that obtained by synthesis. Prometrium acts like a natural hormone produced in our body. In humans, many organs secrete hormones: male and female sexual organs, endocrine glands, central nervous system and others. Accordingly, the hormones may be different, and appoint for a variety of diseases.

Myth 2: Hormones prescribed only in very severe disease
No. There is some minor condition for which is also prescribed hormonal drugs. For example, the reduction of the thyroid gland (hypothyroidism). Doctors often prescribe Prometrium, in this case, for example, thyroxine or eutiroks.

Myth 3: If in time you do not drink the hormonal pill, there is nothing bad will happen
No. Prometrium must be taken strictly according to schedule. For example, the hormonal contraceptive pill is valid for 24 hours. Accordingly, be sure once a day to drink it. Moreover, it is recommended to take Prometrium at the same time. If you drink regularly Prometrium, and once forget to drink it, the required level of the hormone can dramatically decrease.
Here is an example. If a woman has forgotten to drink hormonal contraceptive pill, the next day she should drink in the morning-forgotten night, the evening of that day – yet another pill. If the interval between doses was more than a day (recall that hormonal contraceptive pill is valid for 24 hours), the blood hormone levels will decrease greatly. In response to this will necessarily spotting. In such cases, you can continue taking the pill, but additionally be protected for you next week. If, however, there have been more than 3 days, it is necessary to stop taking hormones, use of other contraception, menstruation and wait for the extra to consult a doctor.

Myth 4: If you take Prometrium, it accumulates in the body
No. When the hormone is absorbed into the body, it immediately breaks down into chemicals, which are then deduced from an organism. For example, the pill is destroyed and the "leaves" from the body during the day: that’s why you need to drink every 24 hours.
However, hormones continue to "work" even after they stopped taking both. But they act indirectly. For example, a woman is drinking a few months hormone pills and then stop taking them, and later she had no problems with the cycle.
Why it is this happening? Hormonal drugs act on different bodies, "target". Need to know: the mechanism of long-acting hormones is not connected to their accumulation in the body. Just this is the principle of action of these drugs ‘work’ in other structures of the body.

Myth 5: Prometrium has side effects, in the first place – weight gain
Drugs completely without side effects is not seen. But we must distinguish the side effects that do not require discontinuation. For example, breast tenderness while taking contraceptive hormones is considered a normal phenomenon. Scanty bleeding in the first or second months of admission to the intermenstrual period, too have the right to be. Headache, dizziness, fluctuations in weight (plus or minus 2 kg) – this is not a sign of pathology or disease. Hormonal drugs administered for a sufficiently long period of time. Organism by the end of the first month adaptable, and everything comes back to normal.
But that was not really serious problems associated with, say, blood vessels, before prescribing medication, and during his acceptance necessarily need to be tested and get tested. Only a doctor can prescribe you a specific hormonal drug that will not harm your health.

Myth 7: Prometrium can always find an alternative
Not always. There are times when Prometrium is indispensable. For example, a woman younger than 50 years have been spayed ovaries. As a result, she quickly becomes older and loses health. In this case, her body up to 55-60 years of age must be hormonal support. Of course, given that its main disease (because of which were spayed) has no contraindications to the appointment.
Capsules are used with estrogen in postmenopausal women with a uterus for the prevention of abnormal thickening of the lining of the uterus (endometrial hyperplasia).

Prometrium Capsules are also used to treat the absence of menstrual periods in women who have previously had a menstrual period (secondary amenorrhea).

Advantages of Prometrium:
    * High contraceptive efficacy.
    * Good tolerance.
    * Availability and ease of use.
    * Adequate control of the menstrual cycle.
    * Reversibility (full recovery of fertility during the 1-12 months)
    * Safety for the majority of somatically healthy women (especially for non-smoking women under age 35)
    * Remove the "fear" in front of an unwanted pregnancy.
    * The ability to "delay" (using monophasic preparations) regular withdrawal bleed response during exams, competitions and recreation (by omitting the 7-day interval, and continue taking the drug in the following packaging method should be discontinued for 3 days before the desired menstrualnopodobnoe reaction is not recommended to resort to the "deferral" of more than 3 cycles in a row).
    * Ability to use mono- drug as the "emergency" contraception (see below).
The benefits of oral contraception should also be considered therapeutic (non-contraceptive), the effects of progestin preparation, namely:
-Regulation of the menstrual cycle (mild algodismenorei, giperpolimenorei, ovulate pain, certain symptoms of premenstrual syndrome),
-Prevention of benign and malignant ovarian tumors, endometrial cancer, cystic mastitis, benign tumors and mammary glands (use this drug for four years or more to 50% reduces the risk of these diseases),
-Prevention of postmenopausal osteoporosis,
-Prevention of uterine fibroids, endometriosis, functional ovarian cysts.

It should be taken daily – one tablet, depending on the treatment goals. It can be applied with or without food. Follow your doctor, even if they are contrary to the instructions provided.

Pharmacological action:
Premarin is an estrogen and contains a mixture of equine estrogens of natural origin (conjugated estrogens), which are similar to endogenous estrogens. In target tissues (organs of female urinary tract, breast and hypothalamus, pituitary) estrogens enter the cell and binding to nuclear estrogen receptors, regulate the synthesis of RNA and protein, causing metabolic effects.
The drug eases and relieves climacteric symptoms associated with estrogen deficiency: vasomotor disorders (including tides) and urogenital symptoms (atrophic vaginitis and atrophic urethritis).

Premarin postmenopausal osteoporosis prevents the development, decreases bone resorption, but does not stimulate bone formation.
The drug increases HDL, lowers LDL and total cholesterol, thereby reducing the risk of cardiovascular disease.
If you are using Premarin as replacement therapy in female hypogonadism or primary ovarian failure noted the appearance of secondary sexual characteristics in patients.

Statement
Premarin is used to treat conditions that occur in women during menopause and menopause.

   – Vasomotor disorders of varying severity caused by estrogen deficiency (hot flashes, sweating);
   – Atrophic vaginitis, atrophic urethritis;
   – Prevention and treatment of osteoporosis caused by estrogen deficiency;
   – Reduced risk of coronary heart disease and associated mortality in postmenopausal women;
   – Gipoestrogenizm female (female hypogonadism or primary ovarian failure).

Dosage and administration
The drug may be appointed as a continuous or intermittent therapy (3 weeks – reception, a week – a break). With continuous therapy Premarin should be taken daily 1 time / day. For women who are postmenopausal treatment can be started at any time.
With vasomotor disturbances, atrophic vaginitis and atrophic urethritis appoint 0.625-1.25 mg / day.
Osteoporosis – to 625 micrograms daily.
When a female hypogonadism and primary ovarian dysfunction – 0.625-1.25 mg / day. The dose is adjusted depending on the severity of symptoms and the endometrium. Doses of 150 mg (used for girls) initiate the development of secondary sexual characteristics.
For the prevention of cardiovascular disease – 0.625-1.25 mg / day.
For patients older sets the minimum dose causing the effect.

Contraindications
   – Proven breast cancer or a suspicion of it;
   – Proven or suspected neoplasm on them;
   – Bleeding from the genital organs of unknown origin;
   – Acute thrombophlebitis and thromboembolism (an indication of the state data in a history related to prior use of estrogen);
   – Proven or suspected pregnancy;
   – Hypersensitivity to the drug.
Pregnancy and lactation
Premarin is contraindicated during pregnancy.
Keep in mind that estrogens are not effective for the treatment and prevention of threatening or habitual abortion.
If necessary, usage Premarin during lactation should decide on the termination of breastfeeding.
Experimental studies have shown that the usage of estrogen during pregnancy is associated with increased risk of birth defects, reproductive system in fetuses of female and male sex, increased risk of vaginal adenosis, squamous cell dysplasia of the cervix and vagina vaginal cancer.

Cautions
Before starting therapy there should be carried out a full survey of the patient, including history taking, measurement of blood pressure, breast examination, abdominal and pelvic organs, performing vaginal smear smear.
With care prescribe the drug to patients with impaired liver function, renal, cardiovascular disease, migraines, asthma, epilepsy, porphyria, hypercalcemia, the risk of thrombosis.
The therapy by Premarin may increase the existing uterine leiomyoma.
Keep in mind that patients with an intact uterus, to reduce the risk of endometrial cancer or hyperplasia Premarin, should be prescribed in combination with progestogen (for 10-14-day course). In addition, you must inform the patient about the need to pass a yearly inspection of the gynecologist. If a patient with an intact uterus is not receiving therapy at the same time progestogen, the survey should also be regular (3-6 months) and must necessarily include endometrial biopsy.
Please note that use of estrogen at higher doses increases the risk of developing breast cancer. However, most studies found no significant correlation between the use of estrogen in normal doses used for replacement therapy and breast cancer.

In the application of Premarin increases the risk of thrombosis, thrombophlebitis and thromboembolism. In the event of complications estrogen therapy should be discontinued.
In the application of Premarin increases the risk of gallbladder disease.
Acceptance of Premarin should be discontinued at least 1 month before the planned surgery and during prolonged immobilization, in order to eliminate the risk of thromboembolism.
Premarin is not a contraceptive.
If you have abnormal vaginal bleeding you should take adequate diagnostic measures (including biopsy to exclude malignancy). If there is no reason to decrease the dose Premarin or intermittent appointment, estrogen therapy may lead to a sharp increase in triglyceride levels of blood plasma with the subsequent development of pancreatitis and other complications in patients with inherited defects in lipoprotein metabolism.
There is no reliable data on the effectiveness of estrogen in the nervous system disorders or depression, which can occur during menopause. It is therefore not recommended to prescribe Premarin for the treatment of these conditions.
The patient should be informed that the resumption of menses on the background of estrogen replacement therapy in postmenopausal women is not a sign of fertility.
It should be noted that the appointment of estrogen for older postmenopausal women with documented coronary heart disease, estrogen therapy does not reduce the overall risk of recurrent coronary heart disease. Therefore, the appointment of Premarin to these patients should be decided individually after evaluating the potential benefits and risks of estrogen therapy.

Results of experimental studies
In studies on laboratory animals there was found that prolonged continuous use of estrogen increases the incidence of carcinoma of the breast, cervix, vagina and liver.

How to enlarge breasts? Not only teenager girls but also adult women worry about this matter, because they are not satisfied with the size of their breasts. They are sure that small breasts are rather unattractive and do not excite the men. It is true that the women who have the third or the fourth breast size attract more men. They have the possibility to wear more sexy dresses, they do not need bras with foam rubber.

Let’s just decide what the women would like to have. So, they want to have volume, sexy, rounded and elastic breast. There are special creams and encapsulated nutritional supplements for breast enhancement. The most popular of them are Quick Bust capsules. They contain 13 components affecting the breast size. This is a non-hormonal kind of medicine, so capsules have no effect on weight. Manufacturers claim that these capsules cause growing of glandular breast tissue. One package consists of 90 capsules. The minus is that their influence is very short. When a woman stops taking the capsules and the breasts reduce to the common natural size again.

Quick Bust capsules for breast enlargement have a large set of ingredients that promote the growth of breast tissue. The unique combination of components of Quick Bust leads to a breast size increasing in three dimensions for 6-9 months.

Many women are not satisfied with the small size, lack of elasticity or sagging of their breasts. Usually the ways of breast improvement require surgery or cost too much cost. Quick Bust is an alternative medicine, which is not only cheaper and safer, but also it doesn’t cause any side effects. Quick Bust stimulates the growth of breast tissue. The drug is effective in any age, it doesn’t depend on initial breast size and physical condition of women.

At puberty, the hormones estrogens start to secrete. It stimulates breast growth. Duration of the period and the number of allocated hormones are responsible for size, shape and fullness of the breast. Shortened puberty or low production of estrogen, prolactin, prostaglandins and progesterone can cause underdevelopment of secondary sexual characteristics, such as breasts. In the post-protubertal period the number hormones affecting breast size reduces and therefore the growth of mammary glands slows down. Quick Bust is safe and recommended for the girls over 13. Quick Bust helps to increase breast tissue, and this medicine does not stimulate production of breast milk.

The next stage in the development of breast tissue occurs during pregnancy and lactation, when it increases also rapidly.

Quick Bust capsules contain only the high quality natural ingredients that are natural steroid phytonutrients. The first changes in the breast tissue growth can be seen after the taking of Quick Bust for two months. At the same time intensifying of the mammary glands growth is accompanied by slight pain or mild discomfort. The chest line increases up to 3 inches (7.5 cm). The result of the drug has no ill effect on the women health, looks naturally and it is a constant.

The Results Quick Bust taking by girls aged 13-21

At this age the desired result is achieved more quickly. A significant increase in mammary glands is observed after Quick Bust taking in less than three months. Noticeable effect can be seen within 30 days of treatment. This age group is characterized small unpleasant effects of Quick Bust taking, for example, pricking and tingling in the breasts. There is also a rapid lip completion, which, however, disappears after the course ending.

The Results of Quick Bust taking by women aged 22-35

At this age the effect of Quick Bust is observed within the period of 60 days. At the same time women have the following effects: the breast size enlargement, the hanging-down reducing, breast wrinkles flattering, lips enlargement. The last one goes away quickly after the course ending. Also the women may notice the increasing of nails and hair growth

The Results of Quick Bust taking by women aged 36-55

At this age the effect of the drug develops slowly. Only a few reports tell about the result achievement in a period of in 30-45 days of Quick Bust taking. However, the positive results have been noticed.

The Results of Quick Bust taking by women over 56

At this age the women are the most sensitive to the stimulation of the pituitary gland, which is due to low hormonal level characteristic of the menopause.

The package form: a plastic bottle with 90 capsules

The treatment method: Take as a dietary food additive, 3 capsules daily during a meal or with a glass of water. Composition: fenugreek extract, palmetto extract, fennel seeds, L-Tyrosine, Mexican wild yam, brown algae powder, Angelica, Damian, woodruff, extract of black cohosh, oat, Knikus, Hops 30. It is recommended to take a daily dose of drug (3 capsules).

Inactive Ingredients: Partially hydrogenated cottonseed oil natural (component is registered in the U.S. Pharmacopoeia), magnesium stearate, peppermint leaf, gelatin.

Do not exceed 9 capsules a day.

The main components of oral contraceptive steroids are artificially created, similar in structure to the female hormones that are produced by the ovaries, estrogen and progesterone.
In our time, the content of hormones in birth control pills reduced compared to the first oral contraceptive. And this in turn has reduced its number of side effects. And now, oral contraceptives are reasonably safe means of protection from unwanted pregnancy. The main function of oral contraceptives is to suppress ovulation – reducing the possibility of an egg to mature and go into the body cavity. In addition to the main action, oral contraceptives have a number of other advantages: preventing failure of the menstrual cycle, and pain during it, the prevention of gynecological diseases, the restoration of reproductive function, the treatment of acne, and, finally, ease of use, lack comfortably in place during intercourse.

Today the market of oral contraceptive products is quite rich. Try to understand. Birth control pills are distinguished by the number of hormones in their composition.

* Combined oral contraceptives (COCs) containing estrogen and progestin (the analog of the hormone progesterone) may be monophasic, i.e. the proportion of estrogen and progestin in each pill is the same. Monophasic contraceptive pilsl found most suitable for most women. Biphasic and triphasic pills differ in different amounts of estrogen and progestin.

* Progestin preparations contain progestin only (minipill). The effectiveness of these pills a little lower, combined, however, they have other advantages improper combination contraceptives. Mini-pill does not affect the milk supply, reduce the risk of thrombosis does not cause a headache, do not cause increased pressure. They are suitable for young mothers and women of mature age, and suffering from frequent headaches. Mini-pill fit highly organized ladies (they must take each day at the same time).

* Postcoital drugs – aimed at preventing unintended pregnancy after unprotected sex. Postcoital contraceptive use, if after sex spent no more than 72 hours. The content of these hormones in contraceptives is very high, which may cause undesirable effects such as bleeding, weakness, nausea. Therefore the use of postcoital drugs is strongly discouraged and is only suitable in cases of emergency. At this point you can use and combination therapy, but be sure to pay attention to the quantitative hormone levels: 50 mg – the first 72 hours are taken two pills 12 hours later another 2, 35 mg – the first 72 hours are taken four tablets in 12 hours more 4. In the presence of progestin preparations (mini-pill) in the first 48 hours to take 20 pills every 12 hours another 20.

In order to find the right pill go to a gynecologist. The doctor will choose the appropriate drug, taking into account the individual characteristics of the organism. In cases of discomfort, any pain, difficulty breathing, rash or yellowness of the skin, increasing the pressure, as well as visual impairment or impending surgery, you should immediately consult a doctor.

One of the most popular combined oral contraceptives is Levonorgestrel ethinyl estradiol.

How to start taking pills from the first package Levonorgestrel ethinyl estradiol?
If last month hormonal contraceptives have been used, start taking the drug Levonorgestrel ethinyl estradiol from the first day of the cycle, i.e. the first day of menstrual bleeding.
If you decided to take drug Levonorgestrel ethinyl estradiol after other COCs, combined with contraceptive vaginal ring or patch, start taking the drug Levonorgestrel ethinyl estradiol next day after you drink the last active pill (the last tablet of the active ingredients) from the current packaging of hormonal contraceptives.

If the packaging of your previous contraceptive contains the inactive pills, throw them and continue to receive the first package of the drug Levonorgestrel ethinyl estradiol, without interruption.
If you have previously used a combined contraceptive vaginal ring or patch, start taking the drug Levonorgestrel ethinyl estradiol daily removal of the ring / patch or follow the advice of a doctor.
In the transition from a purely progestagen contraceptive method (minipill, injection, implant or intrauterine system with the release of progestogen (CPA)) you can take the drug Levonorgestrel ethinyl estradiol with purely progestagen method on any day (with the implant or IUD – the day of their removal; with the injection method – the day on which will be the next scheduled injection), but in all cases within the first 9 days of drug administration Levonorgestrel ethinyl estradiol you should use additional contraceptive measures (e.g., condoms).

Advantages of Levonorgestrel ethinyl estradiol:
* High contraceptive efficacy.
* Good tolerance.
* Availability and ease of use.
* Adequate control of the menstrual cycle.
* Reversibility (full recovery of fertility during the 1-12 months)
* Safety for the majority of somatically healthy women (especially for non-smoking women under age 35)
* Remove the “fear” in front of an unwanted pregnancy.
* The ability to “delay” (using monophasic preparations) regular withdrawal bleed response during exams, competitions and recreation (by omitting the 7-day interval, and continue taking the drug in the following packaging method should be discontinued for 3 days before the desired menstrualnopodobnoe reaction is not recommended to resort to the “deferral” of more than 3 cycles in a row).
* Ability to use mono- drug as the “emergency” contraception (see below).

The benefits of oral contraception should also be considered therapeutic (non-contraceptive), the effects of combined estrogen-progestin preparations, namely:
# Regulation of the menstrual cycle (mild algodismenorei, giperpolimenorei, ovulate pain, certain symptoms of premenstrual syndrome),
# Prevention of benign and malignant ovarian tumors, endometrial cancer, cystic mastitis, benign tumors and mammary glands (use this drug for four years or more to 50% reduces the risk of these diseases),
# Prevention of postmenopausal osteoporosis,
# Prevention of uterine fibroids, endometriosis, functional ovarian cysts.

What is the mechanism of Female cialis action?
Female cialis is an effective, reversible inhibitor selectively acting on phosphodiesterase 5 (PDE5).
Central role in sexual satisfaction is relaxation of cavernous smooth muscle cells of the vagina, which is locally initiated by acetylcholine and nitric oxide, and other physiological agents. Acetylcholine is produced by neurons in the parasympathetic nervous system, nitric oxide and non-cholinergic non-adrenergic neurons released and endothelial cells. The net effect is a suppression of the state of the sympathetic nervous system stimulation or alpha, which causes contraction of smooth muscle cells. Guanosine monophosphate (cGMP) and PDE5 are important for normal sexual satisfaction. cGMP causes the expansion of the arteries, causing blood flow to the erectile tissues.
Blood vessels in the cavernous bodies fill with blood, which causes a decrease in the outflow of blood from the vagina and creating a gradient of blood pressure – a sexual satisfaction. The enzyme PDE5 causes a decrease in the level of cGMP and terminates an erection.

Female cialis inhibits the action of PDE5, thus delaying the decline in the level of cGMP. The level of cGMP in the cavernous bodies allows a woman with erectile dysfunction to have a normal sexual satisfaction.

How effective is Female cialis?
Female cialis, which is taken as needed, up to once per day, improves erectile function in most women suffering from erectile dysfunction of any degree.

Does Female cialis struggle with severe sexual dysfunction?
Yes. In clinical trials, 81% of patients taking Female cialis tablets 20 mg resulted in improved sexual feelings. The study included patients with varying degrees of erectile dysfunction, from mild to severe.

How fast starts and how long it works?
In some women, Female cialis begins to work after 16 minutes. For most patients, this time is 30 minutes. But remember, without sexual stimulation effect does not occur. Effect of Cialis lasts about 36 hours after admission.

The dose of Cialis for healthy middle-aged men is no more than one tablet of Cialis a day. This is Cialis 20mg per day.

Dose and administration:

Female cialis should be taken 15 minutes before the alleged sexual intimacy. However, remember that the maximum concentration of tadalafil in plasma, and hence the maximum lasting effect of Cialis comes in 2 hours after dosing.
Receive Cialis does not depend on the meal.
Willingness to have sex is saved for 36 hours after taking Female cialis.
The maximum dose is recommending – 1 pill Female cialis a day.
Female cialis is a drug designed for women who dream of an intense sexual life. This medicinal product is the result of deep research women’s sexuality. Female cialis results in a 100% satisfaction and is accompanied by the power of unspeakable erotic experiences.
The action of Female cialis is to accelerate blood circulation, thus allows a woman to achieve deeper and more intense orgasms, and also gives an opportunity to feel a woman multiple orgasms in a row.
A Female cialis is produced in the form of a small pink pill form which is identical with the pills for men Viagra and Kamagra. All production takes place under the supervision of the World Health Organization, Boaz (World Health Organization). The drug takes effect in about 30 minutes after administration, and duration of effect varies from 10 to 36 hours. Tablets are available in 100 mg.
Female cialis could be taken with alcohol because it can’t cause a headache attack or non-equilibrium conditions.

The undoubted advantages of the Female cialis lies in the fact that it:
* Eliminates the frustration of sexual desire;
* Increases libido;
* Rejuvenates and strengthens the body and even the ability to reproduce;
* Restores vitality, allowing women to be always on our toes;
* Helps women who are experiencing difficulty in achieving orgasm;
* Helps women experiencing menopause;
* Helps frigid women.

As a result of taking the pills you will have peace of mind, irritability, frustration from the constant disappears without a trace, and the stress and emotional experiences seem in vain. The effect of the Female cialis is achieved by increasing the level of testosterone in the body, which is the key to sexual function.

Natural agent for women can remove all the blocks in the minds of the girls set out the negative factors in life. It will wake up in your beloved a sexual desire, a sensitivity that comes to your senses not immediately.
If you are thinking about how to use a female agent, it is worth it to buy in our store. We buy goods only from approved suppliers who guarantee the quality of their products.
Agents for women have much wider field to use than it might seem at first glance. It is perfect couples or couple who have long been in a relationship, that is, those who could lose the taste for sex with a familiar partner.
Female cialis among other things is able to exert a therapeutic effect. Its use helps to overcome frigidity and also simplify the achievement of orgasm by those who are experiencing this difficulty. The increased blood flow to the female genital organs makes them more susceptible to affection and stimulation.

The composition of oral contraceptives, one component of which is levonorgestrel, are regularly reviewed and changed.

Characterization:
Levonorgestrel is a synthetic analogue of the female hormone progesterone.
In combination with estrogens it is used in combined oral contraceptives and in the hormone replacement therapy.

Pharmacological action
More often levonorgestrel is used as a component of combined oral contraceptives.
It inhibits the release of luteinizing hormone (LH) in the anterior pituitary, resulting in ovulation does not occur. Under the action of the levonorgestrel the mucus changes in the cervix. It becomes denser, which makes the penetration of sperm into the uterus.
Together with estrogen levonorgestrel prevents the physiological process of preparing the endometrium for implantation of a fertilized egg. Levonorgestrel is a synthetic progestin contraceptive with action. It influences on gonadotropic pituitary function, reducing the peak FSH and LH. It causes temporary atrophic changes in the endometrium that lead to disruption of implantation. Increases the viscosity of cervical mucus that impedes the progress of sperm. After S / 6 capsules for implantation, the contraceptive effect is achieved after 24 hours in the Levonorgestrel intrauterine device has a direct local effect on the endometrium (reducing its implantation function), fallopian tubes, the viscosity of cervical mucus, which increases the efficiency and duration of the Navy, without suppression of ovulation.

Contraindications:

Capsules and intrauterine devices: pregnancy, acute and subacute inflammation of the internal and external genitalia, malignant tumors of the body and cervix, metrorrhagia of unknown origin, congenital anomalies of the body and cervix of the uterus, endometriosis, uterine fibroids, chronic endometritis and oophoritis, cervical erosion , ectopic pregnancy (in history), nulliparous women, pregnancy steatosis (in history), acute liver disease, Dubin-Johnson syndrome, rotor syndrome, breast cancer, herpes, and thrombosis of arteries and veins, thromboembolism (history), bleeding of unknown etiology (history), disorders of fat metabolism. Tablets: liver and bile ducts, jaundice (including history).

Precautions:
You should avoid repeated use of the drug inside during the same menstrual cycle due to the possible violation of the menstrual function. You may not use oral lekformy as a means of regular and continuous contraception, as this leads to a lower efficacy and more frequent adverse reactions. At a delay of menstruation for more than 5-7 days after an emergency postcoital contraception is necessary to exclude pregnancy, and in case of uterine bleeding, pelvic examination is recommended.
For adolescents under 16 years of application for emergency postcoital contraception is possible only in exceptional circumstances (including the rape), and only after consulting a gynecologist.

Before installing the Navy to carry out general medical and gynecological examination, include examination of the pelvic organs and breasts, and smear of the cervix, the woman must be re-examined 4-12 weeks after IUD insertion, and then – once in a year or more frequently if clinically indicated. Navy remains effective for five years. You should consult a doctor who has experience with this well-trained Navy or the implementation of this procedure.

Some studies have recently shown that women taking contraceptives containing only progestin, may increase the risk of venous thrombosis, but these results are not definite. However, if symptoms of venous thrombosis appear, you should immediately take appropriate diagnostic and therapeutic measures.

After removal of the IUD fertility is restored in 50% of women after 6 months, at 96.4% – 12 months.

Application
• Levonorgestrel is a part of combined oral contraceptives in a strict dose. Tablets must be taken within three weeks of each day at the same time. This is followed by a seven-day break, after which reception is resumed. During a break, there is menstrual bleeding.

• As the main component of progesterone drugs, which include only levonorgestrel, estrogen available, it should be taken daily at the same time (difference of three hours). Seven-day break is absent. Compared with the combined contraceptive this type of contraception is more effective.

• As a post-coital contraception – contraceptive method based on taking large doses of hormones (estrogen and levonorgestrel) within 72 hours after sexual intercourse without contraception.

• Currently, there is another method of postcoital contraception in which a woman takes only levonorgestrel at a higher dose (750 mg) than in a single tablet progesteron contraceptive.

• As part of hormone replacement therapy (HRT) – estrogen in combination with levonorgestrel used to correct the deficiency of hormones during menopause, accompanied by high tides, frequent obesity. In addition, HRT is the prevention of osteoporosis, cardiovascular disease and Alzheimer’s disease.

• As an intrauterine (IUD) – helix becoming more popular. They are highly effective, but their duration is up to five years. Using the spiral is not accompanied by an increased risk of inflammatory diseases of the pelvic organs.

• Heavy menstruation – intrauterine spirals are used not only for contraception but also to reduce the intensity of menstrual bleeding. Reduced blood loss is achieved by releasing small doses of levonorgestrel, acting on the endometrium.

Dose and administration:

Inside, immediately after the first coitus 1 tablet, with multiple additional 1 tablet at 8 h after the first. You can also receive no more than 4 tablets per month. Capsules of 6 pieces, implanted p / c in the inner part of the shoulder by the original method of surgery, for a period of 5 years. IUD is recommended to enter at 4-6 days of the menstrual cycle after induced abortion or immediately after the next menstrual period. After uncomplicated spontaneous delivery it should be taken no earlier than 6 weeks.

Latin name: Provera

Pharmacological groups: Anti-hormonal and hormone antagonists. Estrogens, progestins, and their homologues and antagonists
The nosological classification (ICD-10): C50 Malignant neoplasm of breast cancer. C54 Malignant neoplasm of corpus uteri. C54.1 endometrium. C64 Malignant neoplasm of kidney, except renal pelvis.

Pharmacological action:

The active substance (INN) Medroxyprogesterone .

(Medroxyprogesterone)
The use of Provera: Contraception, particularly in women of late reproductive age inoperable, recurrent and metastatic carcinoma of the endometrium and kidney (additional palliative therapy), hormone-dependent forms of recurrent breast cancer in postmenopausal period of women.

Inside – secondary amenorrhea, dysfunctional uterine bleeding, premenstrual syndrome, vasomotor symptoms of menopause, endometriosis, the diagnosis of primary and secondary amenorrhea, prevention and treatment of osteoporosis in postmenopauznom period (in combination with estrogen and calcium supplementation), prevention of endometrial changes in replacement therapy estrogen in postmenopausal women.
Contra-Provera: hypersensitivity, thrombophlebitis, thromboembolic syndrome or a history of stroke, liver disease, vaginal bleeding of unspecified etiology, pregnancy, breastfeeding (stop).

Side effects: Menstrual irregularities, thromboembolism, insomnia, irritability, drowsiness, fatigue, weakness, depression, dizziness, headache, edema, nausea, abdominal pain and abdominal discomfort, breast tenderness, galactorrhea, cervical erosion, hirsutism, alopecia , fever, weight change, moon face, osteoporosis, urticaria, pruritus, acne, anaphylaxis and anaphylactoid reactions.

Interaction: aminoglutethimide reduces plasma concentrations and reduces efficiency.

Dosage and administration: V / m, as a contraceptive and for the removal of vasomotor symptoms of menopause – 150 mg 1 time in 3 months, with endometriosis, 50 mg 1 time per week or 100 mg of 1 every 2 weeks course of at least 6 months.
B / B with endometrial cancer or kidney disease – 400-1000 mg weekly, while achieving clinical improvement – 400 mg 1 time per month.

Inside, in endometrial cancer or kidney disease – 200-600 mg / day for breast cancer – 400-1200 mg / day. For the prevention and treatment of osteoporosis in postmenopausal women – from 12-15 to 25 day of the month at 5-10 mg 1 time a day.

Precautions: The first method should be used only on the 5th day of normal menstrual period (guarantee of the absence of pregnancy). You must use an additional contraceptive method for 2 weeks after the first injection. Every three months we recommend an injection of the drug (increased reliability of contraception), when the cycle changes during the reception of required medical consultation. With dysfunctional uterine bleeding necessarily rule out uterine cancer, and other organic lesions. Suspicion for the development of thrombophilic states (thrombophlebitis, cerebrovascular disorders, pulmonary artery branches thromboembolism, renal thrombosis) require immediate repeal. Care must be taken for epilepsy, migraine, asthma, cardiac and renal failure, given the possible delay of the liquid. With care prescribe for patients with diabetes, depression.

Special instructions: The intake of medroxyprogesterone may change the results of laboratory tests (including sulfabromoftaleinovogo and other liver function tests) – reduction of steroids in plasma and urine (progesterone, estradiol, pregnandiol, testosterone, cortisol), gonadotropins, globulin, sex hormone binding, the level of T3, elevated levels of prothrombin, factors VII, VIII, IX, X.

The advantages of injectable contraceptive Provera:
    * High contraceptive efficacy;
    * As a result of contraception there is absolutely no need to worry;
    * Easy to use: Provera is suitable for those women who for one reason or another can not take a daily hormone pills;
    * Provera helps to significantly reduce the risk of inflammatory diseases of the genital organs and ectopic pregnancy;
    * Decrease the frequency of metabolic changes, as the drug does not pass through the liver;
    * Provera provides a therapeutic effect of endometriosis, premenstrual syndrome and menopausal syndrome, some of the menstrual cycle;
    * Provera reduces the intensity of menstruation and menstrual pain;
    * Provera may make breast-feeding women and women with high blood pressure, headaches;
    * Ease of use and privacy: invisible injection, and the fact of birth may be kept secret, that is for some women is extremely important.

First injection of a woman can be done in 3 – 5 days of the menstrual cycle. For those who want to use Provera after birth, the injection should be carried out within five days after delivery for breastfeeding mothers – only 6 weeks. During the first 2 weeks after the first injection of the drug should be used in addition to any non-hormonal contraceptive.
There can be subsequent injections made about once every three months exacted, then every 12 weeks and 5 days. Such regimes are due to the peculiarities of the drug and provide it with maximum efficiency. If for any reason, the injection was not made on time, every time, you must first make sure that the woman is not pregnant, and then "catch up". The next 14 days after the "check" our experts recommend the use of additional methods of contraception, with the exception of other hormones (best fit condom or spermicide).

Women who use Provera, you need to know what injection can be done only in a medical facility by a qualified doctor or nurse. The spot can not be massaged or rubbed, it is better after a couple of hours to spend in a relaxed atmosphere. During the life of the injectable contraceptive, you must strictly adhere to the deadlines, which gynecologists recommend our center to conduct a special calendar, which record the date made and the date of the next injection. There is also a need to make information about the menstrual cycle (duration, amount of bleeding, mood) and show them to your gynecologist.

Today the choice of contraceptives is really great. Every woman has the opportunity to choose from a variety of contraceptives: pills, intrauterine devices, condoms and oral contraceptives. But the most popular and not harmful for women’s health is an oral contraceptive.

Only the doctor-gynecologist may prescribe an adequate method of contraception, especially considering the body of his patient. Oral contraceptive drugs can help normalize the menstrual cycle, improve the color and texture of the skin and to please a number of other pleasant things. In addition, women taking contraceptives, significantly reduces the risk of diseases such as cancer, inflammation of the female genital organs, and the occurrence of future ectopic pregnancy.

The peculiarity of this method of contraception is the regularity of the pills that is to miss or forget about taking oral contraceptives is not possible, because so their effectiveness is significantly reduced. But do not worry about it. If you put a package in a conspicuous place, you will always know that it’s time to take the pills.

If you follow all the instructions on the packaging, it is almost impossible to conceive. The scientists who are engaged in similar studies have shown that out of 10 000 women who took oral contraceptives, became pregnant, only one. And even if an incident occurs – a woman, for whatever reason did not take the pill, the chance of getting pregnant 1 in 100. But remember to drink a tablet may be no more than 3 times in a row, otherwise the whole course losing its accuracy!

Oral contraceptives acts follows: artificial hormones act on the female body in such a way that suppresses ovulation. After that, the egg is not capable of fully mature and, therefore, pregnancy is impossible.

Today’s prerogative among oral contraceptives belongs to Ethinyl Estradiol Norgestrel.

Ethinyl Estradiol Norgestrel (50 mg of Ethinyl Estradol and 0.5 mg of Norestrel) – a combination of estrogen and progesterone, which helps treat a variety of hormonal disorders. Ethinyl Estradiol Norgestrel can be used to postpone menstruation and treatment enodmestrioza, dysmenorrhea (pain during menstruation), urethral bleeding and other menstrual disorders.

Rules of Ethinyl Estradiol Norgestrel admission:

It should be taken daily from 1 to 4 tablets, depending on the treatment goals. It can be applied with or without food. Follow your doctor, even if they are contrary to the instructions provided.

 Overdose:

If you suspect that you have made an overdose, then seek medical help. Among the missed dose overdose symptoms may include: Nausea Vomiting sudden vaginal bleeding if you miss a dose, take medication if you remember. If the short time remains before the next dose, it is better to skip this dose.

Remarks: Ethinyl Estradiol Norgestrel should be applied regularly. Do not use it together with other similar means.

Storage:

Store at room temperature between 15 and 30 degrees Celsius in a dry and dark place. Keep away from children!

Important Notice: This information does not replace a medical examination or doctor’s decision. Not necessarily, that taking this drug will be effective for you. You should consult your doctor.

Frequently Asked Questions – How does Ethinyl Estradiol Norgestrel?

The components of Ethinyl Estradiol Norgestrel affect the hormones responsible for the implementation of the menstrual cycle. They regulate the terms of menstruation and restore the balance.

Is it safe to use Ethinyl Estradiol Norgestrel for pregnant women and nursing mothers?

It is unknown that Ethinyl Estradiol Norgestrel could harm the fetus during pregnancy and newborn baby. If you are pregnant or breast-feeding, you should still consult a doctor to find out about the possible risks to you.

Protect me Ethinyl Estradiol Norgestrel of sexually transmitted infections?

Ethinyl Estradiol Norgestrel does not protect against diseases, sexually transmitted diseases. Use the tools of protection.

Can I prevent pregnancy, taking Ethinyl Estradiol Norgestrel?

Ethinyl Estradiol Norgestrel primarily restores hormonal conditions and can be used to prevent pregnancy.

What is the recommended dose of Ethinyl Estradiol Norgestrel?

The recommended dose of Ethinyl Estradiol Norgestrel is 1 tablet per day, starting with a 20 day menstrual cycle. The recommended dose of Ethinyl Estradiol Norgestrel for the treatment of enomestioza is 1 tablet a day for 6-12 months. The dose may be increased to 2-3 tablets a day. The recommended dose in case of bleeding the urethra is one tablet a day for 20-21 days, starting with the 5 day cycle. If the bleeding stops, dosing can be increased to 2-3 tablets a day. In some cases the dose may be increased to 2-4 tablets a day until the end of the cycle. Then it must be reduced to 1-2 tablets a day. The recommended dose for the treatment of dismonorei one tablet a day, starting with a 5 day cycle. Treatment should continue for 20-21 days, and then interrupted for 7-8 days. For the second cycle, 1 tablet per day, starting at 8 or 9 days. To prevent stomach disorder you should take the drug after meals.

Precautions:

Before using this medication, tell your doctor if you experience: any form of allergy Hypertension, Abnomalnye Pain, Liver problems or current pregnancy, Alleged Recent surgery, prolonged immobility, yellowing of the skin, Vaginal bleeding, Depression Kidney Problems with the thyroid drug, which has as part of the female hormones can be combined with smoking to increase risk of stroke, heart attacks and high blood pressure.

Tell your doctor if you are a nursing mother. If you have recently given birth or within the last 3 months have an abortion, tell your doctor. Tell your doctor if you are using other medications, vitamins and supplements. Do not increase or lower the amount of not talking to your doctor. Thus, according to professors, composition and a unique mode of drug administration Ethinyl Estradiol Norgestrel can be used not only as a medium of contraception, but also for long-term use in most healthy women until the late reproductive age.

Drospirenone (ethinyl estradiol) is the first drug in oral contraceptive that is taken in a 24 +4, that combines 24 days of receiving the active hormone pills plus 4 days of placebo. Innovative dosing regimen designed to avoid fluctuations in the level of female hormones that remain in the traditional mode of reception 7/ 21 (21 active hormone tablets plus 7 days off or 7 days placebo tablets).
The new regimen provides 3 additional days of drospirenone and affirmative action leads to minimization of fluctuations in hormone levels. This eliminates the associated negative symptoms – anxiety, irritability, mood changes, impaired concentration, swelling, headache, breast engorgement, etc. Due to the content of the preparation of such a component, as drospirenone, in particular its antimineralocorticoid properties, the body does not stay liquid (due to the estrogen component), and therefore such symptoms as swelling, weight gain, bloating, breast engorgement do not develop.

Finally, the anti-androgenic properties of drospirenone provide a positive effect on the skin, reducing the activity of the sebaceous glands and as a result, achieved a therapeutic effect in acne.

Drospirenone exhibits no androgenic, estrogenic, glucocorticoid and antiglucocorticoid activity, which in combination with antimineralocorticoid and antiandrogenic properties indicates the similarity of the pharmacological profile of drospirenone and natural hormone progesterone.
In two multicenter, double-blind, randomized, placebo-controlled studies of efficacy and safety of the drug in women with drospirenone acne vulgaris of mild and severe, it was demonstrated clinically and statistically showed significant effect relative to the primary treatment success rates (number of inflammatory and noninflammatory elements, the total number of lesions (elements) and the number and proportion of women with a clear skin, which was assessed on a scale of ISGA (Investigator `s Stated Global Assessment – evaluation scale general state of the researcher), and the majority of secondary indicators.

Thanks to all of the above Drospirenone (ethinyl estradiol) is the only oral contraceptive approved in the country to apply for three indications:
    • Prevention of unwanted pregnancies,
    • treatment of acne (acne) and mild to moderate severity,
    • treatment of emotional and physical symptoms of menstruation period, including the most severe manifestation of them – premenstrual dysphonic disorder (PMDD).

Mode of the drug Drospirenone 24 +4 scheme provides:

•       Abridged non hormonal intervals
•       Decrease hormonal fluctuations
•       Prevention of premenstrual disorders

· Improvement of the skin
Daily admission procedure: due to a placebo pill it is easier to keep track of when to start the next pack Drospirenone (ethinyl estradiol).
Safe and practical:
The company has taken care about the convenience, comfort and safety of a new contraceptive drug Drospirenone (ethinyl estradiol):
    *Each blister pack with Drospirenone (ethinyl estradiol) contraceptive introduced in new packaging, that is in a convenient "envelope", which is comfortably housed in a purse or clutch. Thus, women and girls do not have to hide their pills in the box, and then get them out of it.
    *On one side of "envelope" there is applied the so-called "Rule of the forgotten pills," which will give advice and tell you what to do in case of contraceptive pills Drospirenone reception was omitted, as well as when to take it up next time and what the consequences of such forgetfulness can trap you. Thanks to a new type of packaging as a "purse" is now no need to constantly carry the instructions for use.

In addition, Drospirenone provides reliable protection from unwanted pregnancy; it has also a positive impact on skin condition and general psycho-emotional and physiological state of a woman. The combination of drospirenone with ethinylestradiol improves the content of high-density lipoprotein cholesterol, which favorably affects the cardiovascular system. Thus, according to professors, composition and a unique mode of drug administration Drospirenone can be used not only as a medium of contraception, but also for long-term use in most healthy women until the late reproductive age.

Dosage and administration:
Tablets should be taken daily according to the order specified on the blister, about the same time, with a small amount of liquid. Interruption in the application of tablets Drospirenone does not include. The drug is taken by one tablet per day for 28 days. Tablets from each of the next pack should be started after taking the last pill from the previous package. Menstrual bleeding usually begins at the third day of the placebo pills and can not finish by the beginning of the pills the next pack.

If hormonal contraceptives in the previous period (last month) was not used the tablets should be initiated in 1-day woman’s natural cycle (ie the 1st day of menstrual bleeding). You can start receiving and 5 days, but in this case in the first cycle is recommended to additionally use like a barrier method of contraception for the first 7 days of treatment.

Switching from another combined oral contraceptive (CPC), vaginal ring or transdermal patch is desirable that the woman should start taking the pill Drospirenone on the day after taking the last active pill the previous PDA, but not later than the day after a break in tablet or pill placebo after receiving her previous PDA. In the case of a vaginal ring or transdermal patch is desirable that the woman should start taking Drospirenone to that day, in any case not later than the day when you need the following use of these devices.

Go with a method that is based on the use of only a progestogen ("mini-pill", injections, implants) or intrauterine system with progestogen woman can begin taking the drug Drospirenone every day after discontinuation of the "mini-pill" (in the case of an implant or intrauterine system – on the day of their removal, in the case of injections – rather than following injection). However, in all cases it is recommended to additionally use like a barrier method of contraception for the first 7 days of treatment. Try it and you’ll never regret!

The deep-rooted thrush unlike a random fungal disease is more than just a discomfort: to cure the deep-rooted thrush cure is more difficult than to suppress the symptoms of the traditional thrush.

The causes of the deep-rooted thrush

According to the statistics, approximately five percent of women experience the thrush at least three times a year. Regular symptoms of the thrush say about recurrent vulvo-vaginal candidacies, a state when even with a proper treatment the disease comes back again after a period of time. The causes of the deep-rooted thrush can be very different. This is an incomplete treatment of the fungal infections and poor health (very common the cause of the relapse is diabetes), and prolonged practice of certain drugs.

The deep-rootedthrush’streatment

The deep-rooted thrush is not recommended to treat with the help of the traditional remedies – to suppress the recurrent symptoms much more effective medicines recommended by gynecologist is required.
Although the antifungal drugs, sold at pharmacies without a prescription, are able to cure the thrush in most cases. But they can be a cause of the development of the deep-rooted thrush – because, according to the statistics, two thirds of these drugs are used by women who really do not have the thrush. Improper use or abuse of the antifungal drugs, sold at pharmacies without a prescription, can cause the thrush, which symptoms can not be suppressed with the help of the traditional remedies. In fact, the fungal organisms (in such situation) are developed a kind of “immunity’ to the standard antifungal drugs. That is why it is important to consult a doctor before stating the thrush’s treatment independent.

To diagnose the deep-rooted thrush can make a specialist only. The one specialist who can determine whether symptoms are caused by the uncontrolled multiplication of the fungal organisms or it is a bacterial infection that the reason of the inflammation. A proper diagnosis of deep-rooted thrush is very important, because very different treatments are required for the different types of the infections.

          The deep-rooted thrush’s prevention
The best way to control the deep-rooted thrush is the prevention of the fungal diseases. In order to reduce the risk of the thrush and other fungal diseases, it is necessary to follow a few simple rules:

To refuse too tight clothes, to wear underwear made ​​of natural cotton;

After swimming or any other physical activity, accompanied by sweating, to change the wet clothes to dry and clean immediately;

Do not use flavored personal hygiene products, flavored pads or tampons;

To avoid any products containing fragrances or dyes.

Full info about Vaginal Thrush