Host Responses to Endometriosis

 

HYPERTROPHY AND RELAXATION

 

  1. Uterine and ovarian hypertrophy, leiomyomas
  2. Relaxation of round, uterosacral, utero-ovarian ligaments
  3. Allow uterus and ovaries to adhere to rectovaginal pouch

 

SCLEROSIS OF SOLID ORGANS

 

  1. Uterine sclerosis
  2. Ovarian sclerosis: cartilaginous consistency

 

STENOSIS TO OCCLUSION OF HOLLOW ORGANS

 

  • Cervical stenosis
  • Cornual angle fallopian tube obstruction
  • Perifimbrial tubal stenosis
  • Fimbrial tubal phimosis
  • Ureteral stricture, obstruction
  • Bowel stricture, obstruction

 

  1. INFLAMMATION
  1. Retrograde menstruation
  2. Ruptured endometriomas
  3. Autoimmune changes

 

ADHESIONS

 

  1. Endometriotic adhesions
  2. Surgical adhesions
  3. Adhesions from sexually transmitted diseases
  4. Adhesions from malignancy

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