Cell cultures are the gold standard as specificity approaches 100%. This is essential for medical—legal situations.
Nonculture tests can detect Chlamydia antigens with 97% to 99% specificity.
Direct fluorescent antibody (Micro Trak)
Enzyme immunoassay (Chlamydiazyme)
Nucleic acid hydridization (deoxyribonucleic acid [DNA] probes)
Gold standard of the future
Sensitivity greater than 95%, specificity near 100%
Male and female urine
Swabs: 90% to 100% sensyvity,specifity approaches 100%
Urine: 95% sensitivity
Disadvantages of cell culture.
Requires 3 to 7 days to obtain result
Special transport media and storage temperatures required
Serology is rarely useful in clinical settings for genital tract infections.