Review Parlodel

Parlodel . What is the medication?

 

Parlodel is a peptide ergot alkaloid, dopamine analogue that inhibits the secretion of prolactin selectively, neutralizing lactotropic dopamine receptors on the lactotropic cells of hypophysis.

Treatment with Parlodel is highly effective to treat a form of amenorrhea, provoked by hyperprolactinemia. In overwhelming majority of patients (regardless of whether hyperprolactinemia is associated with pituitary adenoma or not) the drug causes a sharp drop in prolactin level in blood plasma, normal gonadotrophic hypophysary function and ovulatory menstrual cycles recovery.

 

Parlodel Price

 

Parlodel . What are the Therapeutic Indications?

menstrual irregularities, female infertility;

prolactin-dependent deceases and conditions, accompanied or not accompanied by hyperprolactinemia;

hyper-prolactin disorders, caused by the drugs (e.g., certain psychotropic or antihypertensive drugs);

amenorrhea (accompanied and unaccompanied by galactorrhea), oligomenorrhea;

luteal phase defect.

 

Prolactin-dependent female infertility:

Polycystic Ovarian Syndrome;

Anovulatory cycles (in addition to anti-estrogens such as clomiphene).

 

Parlodel . What are the Recommendations for Administration?

Parlodel should always be taken with food. In the case of female infertility it is prescribed per 1.25 mg (1/2 tab.) 2-3 times/day. If the effect is insufficient, the dose is increased gradually up to 5-7.5 mg/day (the dosage frequency is 2-3 times/day). Treatment has to be continued until the ovulation’s recovery.

If necessary, the treatment may be continued for several cycles for secondary prophylaxis.

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